MARRVEL API documentation version v1
http://v1.marrvel.org/data
Home
Welcome to the MARRVEL API Documentation. The MARRVEL API allows you to retrieve the data MARRVEL serves such as OMIM, ExAC, and gnomAD from your application without searching through the web interface.
Please also check Python example if you want to see how to apply API in Python.
/OMIM
OMIM text description of the gene, gene-phenotype relationships, and reported allelic variants.
get
get /OMIM/
Query Parameters
- geneSymbol: required(string)
Specify the gene symbol that you want search from OMIM
Example:
FBXL4
HTTP status code 200
Body
Media type: application/json
Type: object
Properties- mimNumber: required(string)
OMIM identifier, mim number, of the gene
- title: required(string)
Title and symbol, delimited with "";""
- description: required(string)
Text description of the gene
- genePhenoRels: required(array of object)
Items: GenePhenoRel
- phenotypeMap: required(object)
- mimNumber: required(integer)
- phenotype: required(string)
- phenotypeMimNumber: required(integer)
Mim number of the phenotype
- phenotypicSeriesNumber: required(string)
Comma delimited list of phenotypic series numbers
- phenotypeMappingKey: required(integer)
- phenotypeInheritance: required(string)
- phenotypeMap: required(object)
- allelicVariants: required(array of object)
Items: items
- allelicVariant: required(object)
- mimNumber: required(integer)
Mim number of the variant
- status: required(string)
The status of the variant. Either
live,moved, orremoved - name: required(string)
- mutations: required(string)
- text: required(string)
Text description of the variant
- dbSnps: required(string)
Comma delimited list of dbSNPs
- clinvarAccessions: required(string)
Triple semi-colon list of ClinVar accession
- mimNumber: required(integer)
- allelicVariant: required(object)
Example:
{
"allelicVariants":[
{
"allelicVariant":{
"number":1,
"mimNumber":605654,
"status":"live",
"name":"MITOCHONDRIAL DNA DEPLETION SYNDROME 13 (ENCEPHALOMYOPATHIC TYPE)",
"mutations":"FBXL4, GLN519TER",
"text":"In 5 affected members of a highly consanguineous Arabian family with fatal mitochondrial DNA depletion syndrome-13 (MTDPS13; {615471}), {1:Bonnen et al. (2013)} identified a homozygous c.1555C-T transition in the FBXL4 gene, resulting in a gln519-to-ter (Q519X) substitution in the C-terminal LRR domain. The mutation was found by whole-exome sequencing of the proband and showed complete segregation with the disorder in the family. The variant was not present in the NHLBI Exome Sequencing Project or 1000 Genomes Project databases, or in 408 ethnically matched control chromosomes.",
"dbSnps":"rs398123059",
"clinvarAccessions":"RCV000056327"
}
},
{
"allelicVariant":{
"number":2,
"mimNumber":605654,
"status":"live",
"name":"MITOCHONDRIAL DNA DEPLETION SYNDROME 13 (ENCEPHALOMYOPATHIC TYPE)",
"mutations":"FBXL4, ARG435TER",
"text":"In a child, born of consanguineous Arabian parents, with fatal MTDPS13 ({615471}), {1:Bonnen et al. (2013)} identified a homozygous c.1303C-T transition in the FBXL4 gene, resulting in an arg435-to-ter (R435X) substitution. The mutation was found by whole-exome sequencing and segregated with the disorder in the family. The variant was not present in the 1000 Genomes Project database or in 408 ethnically matched controls; it was found in 1 of 13,005 chromosomes in the NHLBI Exome Sequencing Project.",
"dbSnps":"rs201889294",
"clinvarAccessions":"RCV000056328;;;RCV000622490;;;RCV000604628",
"exacDbSnps":"rs201889294"
}
},
{
"allelicVariant":{
"number":3,
"mimNumber":605654,
"status":"live",
"name":"MITOCHONDRIAL DNA DEPLETION SYNDROME 13 (ENCEPHALOMYOPATHIC TYPE)",
"mutations":"FBXL4, GLY568ALA",
"text":"In a 4-year-old boy, born of consanguineous Saudi Arabian parents, with MTDPS13 ({615471}), {3:Gai et al. (2013)} identified a homozygous c.1703G-C transversion in the FBXL4 gene, resulting in a gly568-to-ala (G568A) substitution at a highly conserved residue in the LRR domain. The mutation was found by homozygosity mapping followed by whole-exome sequencing. The mutation was not present in 242 Saudi exomes, in 4,500 in-house European control chromosomes, or in the Exome Variant Server database.",
"dbSnps":"rs398123060",
"clinvarAccessions":"RCV000056329"
}
},
{
"allelicVariant":{
"number":4,
"mimNumber":605654,
"status":"live",
"name":"MITOCHONDRIAL DNA DEPLETION SYNDROME 13 (ENCEPHALOMYOPATHIC TYPE)",
"mutations":"FBXL4, ARG482TRP",
"text":"In 3 sibs, born of consanguineous Saudi Arabian parents, with MTDPS13 ({615471}), {3:Gai et al. (2013)} identified a homozygous c.1444C-T transition in the FBXL4 gene, resulting in an arg482-to-trp (R481W) substitution at a highly conserved residue in the LRR domain. The mutation was found by homozygosity mapping followed by whole-exome sequencing. It was not present in 242 Saudi exomes, in 4,500 in-house European control chromosomes, or in the Exome Variant Server database.",
"dbSnps":"rs398123061",
"clinvarAccessions":"RCV000056330;;;RCV000224233;;;RCV000162170",
"exacDbSnps":"rs398123061"
}
},
{
"allelicVariant":{
"number":5,
"mimNumber":605654,
"status":"live",
"name":"MITOCHONDRIAL DNA DEPLETION SYNDROME 13 (ENCEPHALOMYOPATHIC TYPE)",
"mutations":"FBXL4, ASP565GLY",
"text":"In an Albanian male infant with MTDPS13 ({615471}), {3:Gai et al. (2013)} identified a homozygous c.1694A-G transition in the FBXL4 gene, resulting in an asp565-to-gly (D565G) substitution at a highly conserved residue in the LRR domain. The mutation was found by whole-exome sequencing and was not present in 4,500 in-house European control chromosomes or in the Exome Variant Server database.",
"dbSnps":"rs398123062",
"clinvarAccessions":"RCV000056331"
}
}
],
"mimNumber":605654,
"title":"F-BOX AND LEUCINE-RICH REPEAT PROTEIN 4; FBXL4",
"genePhenoRels":[ ],
"description":"The F box, named after cyclin F (CCNF; <a href=\"http://omim.org/entry/600227\">600227</a>), in which it was originally observed, is an approximately 40-amino acid motif that binds SKP1 (<a href=\"http://omim.org/entry/601434\">601434</a>). F-box proteins, such as FBXL4, are components of modular E3 ubiquitin protein ligases called SCFs (SKP1, cullin (see <a href=\"http://omim.org/entry/603134\">603134</a>), F-box proteins), which function in phosphorylation-dependent ubiquitination.",
"clinVar":[ ]
}
/ExAC
Gene and variant information from ExAC.
get
Search a variant information from ExAC.
get /ExAC/
Search a variant information from ExAC.
Query Parameters
- variant: required(string)
Specify the variant that you want to search from ExAC. In format of
(?:chr|Chr)?([0-9]?[0-9XY])\s*:\s*([0-9]*)\s*([ACGT]*)\s*>\s*([ACGT]*),([0-9]?[0-9XY])\s*-\s*([0-9]*)\s*-\s*([ACGT]*)\s*-\s*([ACGT]*), or.+_0*(\d+)\.\d+:.\.(\d+)([ACGT]*)>([ACGT]*)Example:
Chr6:99365567 T>C
HTTP status code 200
Body
Media type: application/json
Type: object
Properties- ExACalleleCount: required(integer)
Allele count
- ExACalleleNum: required(integer)
Allele number
- ExAChomCount: required(string)
Homozygous count
- ExAChemiCount: required(string)
Hemizygous count
- ExACalleleFreq: required(number)
Allele frequency
- ExACgeneSymbols: required(array of )
genes that the variant falls in
- ExACgeneIds: required(array of )
Ensembl IDs of the genes
- ExAChgncIds: required(array of )
HGNC IDs of the genes
Example:
{
"ExAChomCount":0,
"ExAChemiCount":0,
"ExACalleleFreq":0.000255759,
"ExACalleleCount":30,
"ExACalleleNum":117298,
"ExACgeneSymbols":[
"FBXL4"
],
"ExACgeneIds":[
"ENSG00000112234"
],
"ExAChgncIds":[
13601
]
}
get
Gene information table from ExAC searched by a gene. Please be careful to use this in your application because the structure of the response might be changed in future.
get /ExAC/gene
Gene information table from ExAC searched by a gene. Please be careful to use this in your application because the structure of the response might be changed in future.
Query Parameters
- geneSymbol: required(string)
Specify the gene symbol that you want search from OMIM
Example:
FBXL4
HTTP status code 200
Body
Media type: application/json
Type: object
Properties- ensemblId: required(string)
Ensembl ID of the gene
- symbol: required(string)
Official gene symbol of the gene
- thead: required(array of )
The header row of the table
- tbody: required(array of )
The rows of the table
Example:
{
"ensemblId":"ENSG00000112234",
"symbol":"FBXL4",
"thead":[
"Constraint from ExAC",
"Expected no. variants",
"Observed no. variants",
"ConstraintMetric"
],
"tbody":[
[
"Synonymous",
"71.0",
"77",
"z=-0.44"
],
[
"Missense",
"177.4",
"204",
"z=-0.98"
],
[
"LoF",
"19.2",
"7",
"pLI=0.01"
],
[
"CNV",
"5.3",
"2",
"z=0.59"
]
]
}
/gnomad
Variant information from gnomAD
get
get /gnomad/
Query Parameters
- variant: required(string)
Specify the variant that you want to search from ExAC. In format of
(?:chr|Chr)?([0-9]?[0-9XY])\s*:\s*([0-9]*)\s*([ACGT]*)\s*>\s*([ACGT]*),([0-9]?[0-9XY])\s*-\s*([0-9]*)\s*-\s*([ACGT]*)\s*-\s*([ACGT]*), or.+_0*(\d+)\.\d+:.\.(\d+)([ACGT]*)>([ACGT]*)Example:
Chr6:99365567 T>C
HTTP status code 200
Body
Media type: application/json
Type: object
Properties- allelecount: required(integer)
Allele count
- allelenumber: required(integer)
Allele number
- homozygotes: required(string)
Homozygous count
- allelefrequency: required(number)
Allele frequency
- gene: required(string)
Gene that the variant falls in
- gnomadurl: required(string)
URL to the gnomAD search result page
- gnomADvariant: required(string)
Variant in the gnomAD acceptable format
Example:
{
"allelecount":74,
"allelenumber":270120,
"homozygotes":0,
"allelefrequency":0.000273952,
"gnomadurl":"http://gnomad.broadinstitute.org/variant/6-99365567-T-C",
"gene":"FBXL4",
"gnomADvariant":"6-99365567-T-C"
}
/human
get
get /human/
Query Parameters
- geneSymbol: required(string)
Specify the gene symbol that you want search from OMIM
Example:
FBXL4
HTTP status code 200
Body
Media type: application/json
Type: object
Properties- hgncId: required(string)
HGNC ID of the gene
- entrezId: required(integer)
Entrez Gene ID of the gene
- ensemblId: required(string)
Ensembl ID of the gene
- gos: required(array of object)
GO terms of the gene
Items: items
- goId: required(string)
- goTerms: required(string)
the name of teh GO term
- goTypes: required(integer)
0 if molecular function, 1 if biological process, 2 if celluar component
- expression: required(array of object)
Expression data from Human Atlas
Items: items
- organ: required(string)
- class: required(string)
Expression level. Either
high,medium,low, ornot detected.
- gtex: required(array of object)
Expression data (median RPKM) from GTEx to draw a bar plot
Items: items
- [organ]: required(object)
- name: required(string)
Name of the organ
- x: required(array of )
Tissues of the organ
- y: required(array of )
The median RPKM of the each tissue
- name: required(string)
- [organ]: required(object)
Example:
{
"hgncId":13601,
"entrezId":26235,
"ensemblId":"ENSG00000112234",
"gos":[
{
"goId":"GO:0004842",
"goTerm":"ubiquitin-protein transferase activity",
"goType":0
},
{
"goId":"GO:0005654",
"goTerm":"nucleoplasm",
"goType":2
},
{
"goId":"GO:0005758",
"goTerm":"mitochondrial intermembrane space",
"goType":2
}
],
"expression":[
{
"organ":"adipose tissue",
"class":"not detected"
},
{
"organ":"adrenal gland",
"class":"medium"
},
{
"organ":"appendix",
"class":"medium"
},
{
"organ":"bone marrow",
"class":"high"
},
{
"organ":"breast",
"class":"low"
},
{
"organ":"bronchus",
"class":"medium"
},
{
"organ":"caudate",
"class":"high"
},
{
"organ":"cerebellum",
"class":"high"
},
{
"organ":"cerebral cortex",
"class":"medium"
},
{
"organ":"cervix, uterine",
"class":"medium"
},
{
"organ":"colon",
"class":"medium"
},
{
"organ":"duodenum",
"class":"low"
},
{
"organ":"endometrium",
"class":"medium"
},
{
"organ":"epididymis",
"class":"high"
},
{
"organ":"esophagus",
"class":"medium"
},
{
"organ":"fallopian tube",
"class":"medium"
},
{
"organ":"gallbladder",
"class":"high"
},
{
"organ":"heart muscle",
"class":"medium"
},
{
"organ":"hippocampus",
"class":"high"
},
{
"organ":"kidney",
"class":"medium"
},
{
"organ":"liver",
"class":"low"
},
{
"organ":"lung",
"class":"medium"
},
{
"organ":"lymph node",
"class":"not detected"
},
{
"organ":"nasopharynx",
"class":"high"
},
{
"organ":"oral mucosa",
"class":"low"
},
{
"organ":"ovary",
"class":"low"
},
{
"organ":"pancreas",
"class":"medium"
},
{
"organ":"parathyroid gland",
"class":"medium"
},
{
"organ":"placenta",
"class":"medium"
},
{
"organ":"prostate",
"class":"high"
},
{
"organ":"rectum",
"class":"high"
},
{
"organ":"salivary gland",
"class":"medium"
},
{
"organ":"seminal vesicle",
"class":"medium"
},
{
"organ":"skeletal muscle",
"class":"low"
},
{
"organ":"skin",
"class":"medium"
},
{
"organ":"small intestine",
"class":"medium"
},
{
"organ":"smooth muscle",
"class":"medium"
},
{
"organ":"soft tissue",
"class":"medium"
},
{
"organ":"spleen",
"class":"low"
},
{
"organ":"stomach",
"class":"high"
},
{
"organ":"testis",
"class":"medium"
},
{
"organ":"thyroid gland",
"class":"low"
},
{
"organ":"tonsil",
"class":"medium"
},
{
"organ":"urinary bladder",
"class":"high"
},
{
"organ":"vagina",
"class":"low"
}
],
"gtex":{
"Adipose":{
"x":[
"Subcutaneous",
"Visceral"
],
"y":[
3.21,
2.914
],
"marker":{
"color":[
"hsl(0,50%,50%)",
"hsl(0,50%,50%)"
]
},
"name":"Adipose",
"visible":true,
"type":"bar"
},
"Adrenal Gland":{
"x":[
"Adrenal Gland"
],
"y":[
3.869
],
"marker":{
"color":[
"hsl(348,50%,50%)"
]
},
"name":"Adrenal Gland",
"visible":true,
"type":"bar"
},
"Artery":{
"x":[
"Aorta",
"Coronary",
"Artery - Tibial"
],
"y":[
3.117,
2.552,
2.499
],
"marker":{
"color":[
"hsl(24,50%,50%)",
"hsl(24,50%,50%)",
"hsl(24,50%,50%)"
]
},
"name":"Artery",
"visible":true,
"type":"bar"
},
"Bladder":{
"x":[
"Bladder"
],
"y":[
3.517
],
"marker":{
"color":[
"hsl(324,50%,50%)"
]
},
"name":"Bladder",
"visible":true,
"type":"bar"
},
"Brain":{
"x":[
"Amygdala",
"Anterior cingulate cortex",
"Caudate",
"Cerebellar Hemisphere",
"Cerebellum",
"Brain - Cortex",
"Frontal Cortex",
"Hippocampus",
"Hypothalamus",
"Nucleus accumbens",
"Putamen",
"Spinal cord",
"Substantia nigra"
],
"y":[
1.358,
1.193,
1.386,
2.294,
2.189,
1.243,
1.437,
1.474,
1.822,
1.44,
1.232,
2.273,
1.676
],
"marker":{
"color":[
"hsl(48,50%,50%)",
"hsl(48,50%,50%)",
"hsl(48,50%,50%)",
"hsl(48,50%,50%)",
"hsl(48,50%,50%)",
"hsl(48,50%,50%)",
"hsl(48,50%,50%)",
"hsl(48,50%,50%)",
"hsl(48,50%,50%)",
"hsl(48,50%,50%)",
"hsl(48,50%,50%)",
"hsl(48,50%,50%)",
"hsl(48,50%,50%)"
]
},
"name":"Brain",
"visible":true,
"type":"bar"
},
"Breast":{
"x":[
"Mammary Tissue"
],
"y":[
3.232
],
"marker":{
"color":[
"hsl(300,50%,50%)"
]
},
"name":"Breast",
"visible":true,
"type":"bar"
},
"Cells":{
"x":[
"EBV",
"Transformed fibroblasts"
],
"y":[
3.361,
3.736
],
"marker":{
"color":[
"hsl(72,50%,50%)",
"hsl(72,50%,50%)"
]
},
"name":"Cells",
"visible":true,
"type":"bar"
},
"Cervix":{
"x":[
"Ectocervix",
"Endocervix"
],
"y":[
2.986,
3.496
],
"marker":{
"color":[
"hsl(276,50%,50%)",
"hsl(276,50%,50%)"
]
},
"name":"Cervix",
"visible":true,
"type":"bar"
},
"Colon":{
"x":[
"Sigmoid",
"Transverse"
],
"y":[
2.515,
2.297
],
"marker":{
"color":[
"hsl(96,50%,50%)",
"hsl(96,50%,50%)"
]
},
"name":"Colon",
"visible":true,
"type":"bar"
},
"Esophagus":{
"x":[
"Gastroesophageal Junction",
"Mucosa",
"Muscularis"
],
"y":[
2.122,
2.021,
2.097
],
"marker":{
"color":[
"hsl(252,50%,50%)",
"hsl(252,50%,50%)",
"hsl(252,50%,50%)"
]
},
"name":"Esophagus",
"visible":true,
"type":"bar"
},
"Fallopian Tube":{
"x":[
"Fallopian Tube"
],
"y":[
2.691
],
"marker":{
"color":[
"hsl(120,50%,50%)"
]
},
"name":"Fallopian Tube",
"visible":true,
"type":"bar"
},
"Heart":{
"x":[
"Atrial Appendage",
"Left Ventricle"
],
"y":[
1.905,
1.268
],
"marker":{
"color":[
"hsl(228,50%,50%)",
"hsl(228,50%,50%)"
]
},
"name":"Heart",
"visible":true,
"type":"bar"
},
"Kidney":{
"x":[
"Kidney - Cortex"
],
"y":[
2.361
],
"marker":{
"color":[
"hsl(144,50%,50%)"
]
},
"name":"Kidney",
"visible":true,
"type":"bar"
},
"Liver":{
"x":[
"Liver"
],
"y":[
2.106
],
"marker":{
"color":[
"hsl(204,50%,50%)"
]
},
"name":"Liver",
"visible":true,
"type":"bar"
},
"Lung":{
"x":[
"Lung"
],
"y":[
2.641
],
"marker":{
"color":[
"hsl(168,50%,50%)"
]
},
"name":"Lung",
"visible":true,
"type":"bar"
},
"Minor Salivary Gland":{
"x":[
"Minor Salivary Gland"
],
"y":[
3.267
],
"marker":{
"color":[
"hsl(180,50%,50%)"
]
},
"name":"Minor Salivary Gland",
"visible":true,
"type":"bar"
},
"Muscle":{
"x":[
"Skeletal"
],
"y":[
2.057
],
"marker":{
"color":[
"hsl(192,50%,50%)"
]
},
"name":"Muscle",
"visible":true,
"type":"bar"
},
"Nerve":{
"x":[
"Nerve - Tibial"
],
"y":[
5.201
],
"marker":{
"color":[
"hsl(156,50%,50%)"
]
},
"name":"Nerve",
"visible":true,
"type":"bar"
},
"Ovary":{
"x":[
"Ovary"
],
"y":[
3.588
],
"marker":{
"color":[
"hsl(216,50%,50%)"
]
},
"name":"Ovary",
"visible":true,
"type":"bar"
},
"Pancreas":{
"x":[
"Pancreas"
],
"y":[
2.617
],
"marker":{
"color":[
"hsl(132,50%,50%)"
]
},
"name":"Pancreas",
"visible":true,
"type":"bar"
},
"Pituitary":{
"x":[
"Pituitary"
],
"y":[
2.713
],
"marker":{
"color":[
"hsl(240,50%,50%)"
]
},
"name":"Pituitary",
"visible":true,
"type":"bar"
},
"Prostate":{
"x":[
"Prostate"
],
"y":[
2.983
],
"marker":{
"color":[
"hsl(108,50%,50%)"
]
},
"name":"Prostate",
"visible":true,
"type":"bar"
},
"Skin":{
"x":[
"Skin - Not Sun Exposed",
"Skin - Sun Exposed"
],
"y":[
2.793,
2.721
],
"marker":{
"color":[
"hsl(264,50%,50%)",
"hsl(264,50%,50%)"
]
},
"name":"Skin",
"visible":true,
"type":"bar"
},
"Small Intestine":{
"x":[
"Terminal Ileum"
],
"y":[
2.444
],
"marker":{
"color":[
"hsl(84,50%,50%)"
]
},
"name":"Small Intestine",
"visible":true,
"type":"bar"
},
"Spleen":{
"x":[
"Spleen"
],
"y":[
2.365
],
"marker":{
"color":[
"hsl(288,50%,50%)"
]
},
"name":"Spleen",
"visible":true,
"type":"bar"
},
"Stomach":{
"x":[
"Stomach"
],
"y":[
2.753
],
"marker":{
"color":[
"hsl(60,50%,50%)"
]
},
"name":"Stomach",
"visible":true,
"type":"bar"
},
"Testis":{
"x":[
"Testis"
],
"y":[
1.694
],
"marker":{
"color":[
"hsl(312,50%,50%)"
]
},
"name":"Testis",
"visible":true,
"type":"bar"
},
"Thyroid":{
"x":[
"Thyroid"
],
"y":[
3.867
],
"marker":{
"color":[
"hsl(36,50%,50%)"
]
},
"name":"Thyroid",
"visible":true,
"type":"bar"
},
"Uterus":{
"x":[
"Uterus"
],
"y":[
3.2
],
"marker":{
"color":[
"hsl(336,50%,50%)"
]
},
"name":"Uterus",
"visible":true,
"type":"bar"
},
"Vagina":{
"x":[
"Vagina"
],
"y":[
3.002
],
"marker":{
"color":[
"hsl(12,50%,50%)"
]
},
"name":"Vagina",
"visible":true,
"type":"bar"
},
"Whole Blood":{
"x":[
"Whole Blood"
],
"y":[
0.9704
],
"marker":{
"color":[
"hsl(360,50%,50%)"
]
},
"name":"Whole Blood",
"visible":true,
"type":"bar"
}
}
}
/homolog
get
Get the predicted worm orthologs of a human gene
get /homolog/worm
Get the predicted worm orthologs of a human gene
Query Parameters
- geneSymbol: required(string)
Specify the human gene symbol that you want to get worm ortholog of
Example:
FBXL4
HTTP status code 200
Body
Media type: application/json
Type: array of object
Items: items
- geneSymbol: required(string)
gene symbol of the ortholog worm gene
- geneId: required(string)
WormBase ID of the worm gene
- entrezId: required(integer)
Entrez Gene ID of the worm gene
- dioptScore: required(integer)
DIOPT score that indicates the number of individual ortholog prediction tools that report a given ortholog pair. Maximum 12.
- bestScore: required(boolean)
if this ortholog pair has best scores among all the pairs then
true, otherwise,false. - goTerms: required(array of object)
Experiment based GO terms
Items: items
- goId: required(string)
- goTerms: required(string)
the name of the GO term
- goTypes: required(integer)
0 if molecular function, 1 if biological process, 2 if celluar component
Example:
[
{
"geneSymbol":"duo-3",
"geneId":"WBGene00001112",
"entrezId":172925,
"dioptScore":1,
"bestScore":true,
"goTerms":[
{
"goId":"GO:0016579",
"goTerm":"NOTprotein deubiquitination",
"goType":1
},
{
"goId":"GO:0036459",
"goTerm":"thiol-dependent ubiquitinyl hydrolase activity",
"goType":0
}
],
"expression":[
]
},
{
"geneSymbol":"Y71A12B.12",
"geneId":"WBGene00013509",
"entrezId":173263,
"dioptScore":1,
"bestScore":true,
"goTerms":[
],
"expression":[
]
}
]
get
Get the predicted budding yeast orthologs of a human gene
get /homolog/buddingYeast
Get the predicted budding yeast orthologs of a human gene
Query Parameters
- geneSymbol: required(string)
Specify the human gene symbol that you want to get budding yeast ortholog of
Example:
FBXL4
HTTP status code 200
Body
Media type: application/json
Type: array of object
Items: items
- geneSymbol: required(string)
gene symbol of the ortholog budding yeast gene
- geneId: required(string)
SGD ID of the yeast gene
- entrezId: required(integer)
Entrez Gene ID of the yeast gene
- dioptScore: required(integer)
DIOPT score that indicates the number of individual ortholog prediction tools that report a given ortholog pair. Maximum 11.
- bestScore: required(boolean)
if this ortholog pair has best scores among all the pairs then
true, otherwise,false. - goTerms: required(array of object)
Experiment based GO terms
Items: items
- goId: required(string)
- goTerms: required(string)
the name of the GO term
- goTypes: required(integer)
0 if molecular function, 1 if biological process, 2 if celluar component
Example:
[
{
"geneSymbol":"GRR1",
"geneId":"S000003850",
"entrezId":853552,
"dioptScore":2,
"bestScore":true,
"goTerms":[
{
"goId":"GO:0000142",
"goTerm":"cellular bud neck contractile ring",
"goType":2
},
{
"goId":"GO:0000209",
"goTerm":"protein polyubiquitination",
"goType":1
},
{
"goId":"GO:0000751",
"goTerm":"mitotic cell cycle arrest in response to pheromone",
"goType":1
},
{
"goId":"GO:0004842",
"goTerm":"ubiquitin-protein transferase activity",
"goType":0
},
{
"goId":"GO:0005634",
"goTerm":"nucleus",
"goType":2
},
{
"goId":"GO:0005737",
"goTerm":"cytoplasm",
"goType":2
},
{
"goId":"GO:0006974",
"goTerm":"cellular response to DNA damage stimulus",
"goType":1
},
{
"goId":"GO:0016567",
"goTerm":"protein ubiquitination",
"goType":1
},
{
"goId":"GO:0019005",
"goTerm":"SCF ubiquitin ligase complex",
"goType":2
},
{
"goId":"GO:0030674",
"goTerm":"protein binding, bridging",
"goType":0
},
{
"goId":"GO:0031146",
"goTerm":"SCF-dependent proteasomal ubiquitin-dependent protein catabolic process",
"goType":1
},
{
"goId":"GO:0071406",
"goTerm":"cellular response to methylmercury",
"goType":1
}
],
"expression":[
]
},
{
"geneSymbol":"UBP8",
"geneId":"S000004836",
"entrezId":855263,
"dioptScore":1,
"bestScore":false,
"goTerms":[
{
"goId":"GO:0000124",
"goTerm":"SAGA complex",
"goType":2
},
{
"goId":"GO:0004843",
"goTerm":"NOTthiol-dependent ubiquitin-specific protease activity",
"goType":0
},
{
"goId":"GO:0008380",
"goTerm":"RNA splicing",
"goType":1
},
{
"goId":"GO:0016578",
"goTerm":"histone deubiquitination",
"goType":1
},
{
"goId":"GO:0032947",
"goTerm":"protein complex scaffold",
"goType":0
},
{
"goId":"GO:0034729",
"goTerm":"histone H3-K79 methylation",
"goType":1
},
{
"goId":"GO:0046695",
"goTerm":"SLIK (SAGA-like) complex",
"goType":2
},
{
"goId":"GO:0051568",
"goTerm":"histone H3-K4 methylation",
"goType":1
},
{
"goId":"GO:0071819",
"goTerm":"DUBm complex",
"goType":2
}
],
"expression":[
]
},
{
"geneSymbol":"RAD7",
"geneId":"S000003813",
"entrezId":853512,
"dioptScore":1,
"bestScore":false,
"goTerms":[
{
"goId":"GO:0000113",
"goTerm":"nucleotide-excision repair factor 4 complex",
"goType":2
},
{
"goId":"GO:0000715",
"goTerm":"nucleotide-excision repair, DNA damage recognition",
"goType":1
},
{
"goId":"GO:0003684",
"goTerm":"damaged DNA binding",
"goType":0
},
{
"goId":"GO:0004842",
"goTerm":"ubiquitin-protein transferase activity",
"goType":0
},
{
"goId":"GO:0008094",
"goTerm":"DNA-dependent ATPase activity",
"goType":0
},
{
"goId":"GO:0031463",
"goTerm":"Cul3-RING ubiquitin ligase complex",
"goType":2
},
{
"goId":"GO:0034613",
"goTerm":"cellular protein localization",
"goType":1
},
{
"goId":"GO:0042787",
"goTerm":"protein ubiquitination involved in ubiquitin-dependent protein catabolic process",
"goType":1
}
],
"expression":[
]
},
{
"geneSymbol":"AMN1",
"geneId":"S000000362",
"entrezId":852455,
"dioptScore":1,
"bestScore":true,
"goTerms":[
{
"goId":"GO:0001100",
"goTerm":"negative regulation of exit from mitosis",
"goType":1
},
{
"goId":"GO:0005515",
"goTerm":"protein binding",
"goType":0
},
{
"goId":"GO:0005634",
"goTerm":"nucleus",
"goType":2
},
{
"goId":"GO:0005737",
"goTerm":"cytoplasm",
"goType":2
},
{
"goId":"GO:0005933",
"goTerm":"cellular bud",
"goType":2
},
{
"goId":"GO:0007093",
"goTerm":"mitotic cell cycle checkpoint",
"goType":1
}
],
"expression":[
]
}
]
get
Get the predicted fly orthologs of a human gene
get /homolog/drosophila
Get the predicted fly orthologs of a human gene
Query Parameters
- geneSymbol: required(string)
Specify the human gene symbol that you want to get fly ortholog of
Example:
FBXL4
HTTP status code 200
Body
Media type: application/json
Type: array of object
Items: items
- geneSymbol: required(string)
gene symbol of the ortholog fly gene
- geneId: required(string)
FlyBase ID of the fly gene
- entrezId: required(integer)
Entrez Gene ID of the fly gene
- dioptScore: required(integer)
DIOPT score that indicates the number of individual ortholog prediction tools that report a given ortholog pair. Maximum 12.
- bestScore: required(boolean)
if this ortholog pair has best scores among all the pairs then
true, otherwise,false. - goTerms: required(array of object)
Experiment based GO terms
Items: items
- goId: required(string)
- goTerms: required(string)
the name of the GO term
- goTypes: required(integer)
0 if molecular function, 1 if biological process, 2 if celluar component
- expression: required(object)
- tissueId: required(string)
- description: required(string)
name of the tissue
- flybaseId: required(string)
- expLevel: required(number)
expression level of the tissue
- heatmapClass: required(integer)
If adult
1,2otherwise.
Example:
[
{
"geneSymbol":"Fbxl4",
"geneId":"FBgn0030555",
"entrezId":32378,
"dioptScore":10,
"bestScore":true,
"goTerms":[
{
"goId":"GO:0016059",
"goTerm":"deactivation of rhodopsin mediated signaling",
"goType":1
}
],
"expression":[
{
"tissueId":"AT_001",
"flybaseId":"FBgn0030555",
"expLevel":335.3,
"heatmapClass":3,
"affy2ProbSetPrefix":"162",
"description":"Head",
"type":"AT",
"organTissueId":1
}
]
}
]
get
Get the predicted fission yeast orthologs of a human gene
get /homolog/fissionYeast
Get the predicted fission yeast orthologs of a human gene
Query Parameters
- geneSymbol: required(string)
Specify the human gene symbol that you want to get fission yeast ortholog of
Example:
CDK2
HTTP status code 200
Body
Media type: application/json
Type: array of object
Items: items
- geneSymbol: required(string)
gene symbol of the ortholog fission yeast gene
- geneId: required(string)
PomBase ID of the fission yeast gene
- entrezId: required(integer)
Entrez Gene ID of the fission yeast gene
- dioptScore: required(integer)
DIOPT score that indicates the number of individual ortholog prediction tools that report a given ortholog pair. Maximum 8.
- bestScore: required(boolean)
if this ortholog pair has best scores among all the pairs then
true, otherwise,false. - goTerms: required(array of object)
Experiment based GO terms
Items: items
- goId: required(string)
- goTerms: required(string)
the name of the GO term
- goTypes: required(integer)
0 if molecular function, 1 if biological process, 2 if celluar component
Example:
[
{
"geneSymbol":"cdc2",
"geneId":"SPBC11B10.09",
"entrezId":2539869,
"dioptScore":6,
"bestScore":true,
"goTerms":[ ],
"expression":[
]
},
{
"geneSymbol":"pef1",
"geneId":"SPCC16C4.11",
"entrezId":2539366,
"dioptScore":3,
"bestScore":false,
"goTerms":[
{
"goId":"GO:0000083",
"goTerm":"regulation of transcription involved in G1/S transition of mitotic cell cycle",
"goType":1
},
{
"goId":"GO:0005634",
"goTerm":"nucleus",
"goType":2
},
{
"goId":"GO:0005829",
"goTerm":"cytosol",
"goType":2
},
{
"goId":"GO:0007089",
"goTerm":"traversing start control point of mitotic cell cycle",
"goType":1
},
{
"goId":"GO:0007165",
"goTerm":"signal transduction",
"goType":1
},
{
"goId":"GO:0042764",
"goTerm":"ascospore-type prospore",
"goType":2
}
],
"expression":[
]
},
{
"geneSymbol":"lsk1",
"geneId":"SPAC2F3.15",
"entrezId":2541672,
"dioptScore":1,
"bestScore":false,
"goTerms":[
{
"goId":"GO:0000790",
"goTerm":"nuclear chromatin",
"goType":2
},
{
"goId":"GO:0005634",
"goTerm":"nucleus",
"goType":2
},
{
"goId":"GO:0005730",
"goTerm":"nucleolus",
"goType":2
},
{
"goId":"GO:0019908",
"goTerm":"nuclear cyclin-dependent protein kinase holoenzyme complex",
"goType":2
},
{
"goId":"GO:0036278",
"goTerm":"positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation",
"goType":2
},
{
"goId":"GO:0070692",
"goTerm":"CTDK-1 complex",
"goType":2
},
{
"goId":"GO:0071619",
"goTerm":"phosphorylation of RNA polymerase II C-terminal domain serine 2 residues",
"goType":0
},
{
"goId":"GO:1904788",
"goTerm":"positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promo",
"goType":0
},
{
"goId":"GO:1904789",
"goTerm":"regulation of mitotic actomyosin contractile ring maintenance",
"goType":2
}
],
"expression":[
]
},
{
"geneSymbol":"srb10",
"geneId":"SPAC23H4.17c",
"entrezId":2541900,
"dioptScore":1,
"bestScore":false,
"goTerms":[
{
"goId":"GO:0006357",
"goTerm":"regulation of transcription from RNA polymerase II promoter",
"goType":1
},
{
"goId":"GO:0010971",
"goTerm":"positive regulation of G2/M transition of mitotic cell cycle",
"goType":1
},
{
"goId":"GO:0016592",
"goTerm":"mediator complex",
"goType":2
},
{
"goId":"GO:0070816",
"goTerm":"phosphorylation of RNA polymerase II C-terminal domain",
"goType":1
},
{
"goId":"GO:1900387",
"goTerm":"negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter",
"goType":1
}
],
"expression":[
]
},
{
"geneSymbol":"ppk23",
"geneId":"SPBC18H10.15",
"entrezId":2540799,
"dioptScore":1,
"bestScore":false,
"goTerms":[
{
"goId":"GO:0005634",
"goTerm":"nucleus",
"goType":2
}
],
"expression":[
]
}
]
get
Get the predicted zebrafish orthologs of a human gene
get /homolog/zebrafish
Get the predicted zebrafish orthologs of a human gene
Query Parameters
- geneSymbol: required(string)
Specify the human gene symbol that you want to get zebrafish ortholog of
Example:
FBXL4
HTTP status code 200
Body
Media type: application/json
Type: array of object
Items: items
- geneSymbol: required(string)
gene symbol of the ortholog zebrafish gene
- geneId: required(string)
ZFIN ID of the zebrafish gene
- entrezId: required(integer)
Entrez Gene ID of the zebrafish gene
- dioptScore: required(integer)
DIOPT score that indicates the number of individual ortholog prediction tools that report a given ortholog pair. Maximum 12.
- bestScore: required(boolean)
if this ortholog pair has best scores among all the pairs then
true, otherwise,false. - goTerms: required(array of object)
Experiment based GO terms
Items: items
- goId: required(string)
- goTerms: required(string)
the name of the GO term
- goTypes: required(integer)
0 if molecular function, 1 if biological process, 2 if celluar component
Example:
[
{
"geneSymbol":"fbxl4",
"geneId":"ZDB-GENE-041114-187",
"entrezId":492349,
"dioptScore":9,
"bestScore":true,
"goTerms":[
],
"expression":[
{
"tissueId":"ZFA:0001094",
"zfinId":"ZDB-GENE-041114-187",
"description":"whole organism"
}
]
},
{
"geneSymbol":"kdm2aa",
"geneId":"ZDB-GENE-061215-144",
"entrezId":571851,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
]
},
{
"geneSymbol":"kdm2ab",
"geneId":"ZDB-GENE-101007-5",
"entrezId":799441,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
]
},
{
"geneSymbol":"fbxl17",
"geneId":"ZDB-GENE-111013-3",
"entrezId":795023,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
]
},
{
"geneSymbol":"fbxl15",
"geneId":"ZDB-GENE-040426-2440",
"entrezId":405878,
"dioptScore":1,
"bestScore":false,
"goTerms":[
{
"goId":"GO:0009953",
"goTerm":"dorsal/ventral pattern formation",
"goType":1
}
],
"expression":[
{
"tissueId":"ZFA:0001094",
"zfinId":"ZDB-GENE-040426-2440",
"description":"whole organism"
},
{
"tissueId":"ZFA:0001114",
"zfinId":"ZDB-GENE-040426-2440",
"description":"head"
}
]
},
{
"geneSymbol":"zgc:158376",
"geneId":"ZDB-GENE-070720-8",
"entrezId":100101643,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
]
},
{
"geneSymbol":"fbxl6",
"geneId":"ZDB-GENE-060810-162",
"entrezId":323163,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
{
"tissueId":"ZFA:0001094",
"zfinId":"ZDB-GENE-060810-162",
"description":"whole organism"
}
]
},
{
"geneSymbol":"si:dkey-192l18.9",
"geneId":"ZDB-GENE-120709-25",
"entrezId":100005961,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
]
}
]
get
Get the predicted mouse orthologs of a human gene
get /homolog/mouse
Get the predicted mouse orthologs of a human gene
Query Parameters
- geneSymbol: required(string)
Specify the human gene symbol that you want to get mouse ortholog of
Example:
FBXL4
HTTP status code 200
Body
Media type: application/json
Type: array of object
Items: items
- geneSymbol: required(string)
gene symbol of the ortholog mouse gene
- geneId: required(string)
MGI ID of the mouse gene
- entrezId: required(integer)
Entrez Gene ID of the mouse gene
- dioptScore: required(integer)
DIOPT score that indicates the number of individual ortholog prediction tools that report a given ortholog pair. Maximum 13.
- bestScore: required(boolean)
if this ortholog pair has best scores among all the pairs then
true, otherwise,false. - goTerms: required(array of object)
Experiment based GO terms
Items: items
- goId: required(string)
- goTerms: required(string)
the name of the GO term
- goTypes: required(integer)
0 if molecular function, 1 if biological process, 2 if celluar component
- expression: required(array of object)
Wild type expression information
Items: items
- tissueId: required(string)
- mgiId: required(string)
- description: required(string)
Tissue name
Example:
[
{
"geneSymbol":"Fbxl4",
"geneId":"2140367",
"entrezId":"269514",
"dioptScore":11,
"bestScore":true,
"goTerms":[
],
"expression":[
]
},
{
"geneSymbol":"Fbxl17",
"geneId":"1354704",
"entrezId":"50758",
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
{
"tissueId":"EMAPA:16469",
"mgiId":1354704,
"expType":1,
"description":"nervous system"
}
]
},
{
"geneSymbol":"Kdm2a",
"geneId":"1354736",
"entrezId":"225876",
"dioptScore":1,
"bestScore":false,
"goTerms":[
{
"goId":"GO:0000790",
"goTerm":"nuclear chromatin",
"goType":2
},
{
"goId":"GO:0001701",
"goTerm":"in utero embryonic development",
"goType":1
},
{
"goId":"GO:0001843",
"goTerm":"neural tube closure",
"goType":1
},
{
"goId":"GO:0001947",
"goTerm":"heart looping",
"goType":1
},
{
"goId":"GO:0010628",
"goTerm":"positive regulation of gene expression",
"goType":1
},
{
"goId":"GO:0010629",
"goTerm":"negative regulation of gene expression",
"goType":1
},
{
"goId":"GO:0030182",
"goTerm":"neuron differentiation",
"goType":1
},
{
"goId":"GO:0033184",
"goTerm":"positive regulation of histone ubiquitination",
"goType":1
},
{
"goId":"GO:0035264",
"goTerm":"multicellular organism growth",
"goType":1
},
{
"goId":"GO:0043066",
"goTerm":"negative regulation of apoptotic process",
"goType":1
},
{
"goId":"GO:0045322",
"goTerm":"unmethylated CpG binding",
"goType":0
},
{
"goId":"GO:0060563",
"goTerm":"neuroepithelial cell differentiation",
"goType":1
}
],
"expression":[
{
"tissueId":"EMAPA:16405",
"mgiId":1354736,
"expType":1,
"description":"limbs"
},
{
"tissueId":"EMAPA:16469",
"mgiId":1354736,
"expType":1,
"description":"nervous system"
}
]
},
{
"geneSymbol":"Fbxl19",
"geneId":"3039600",
"entrezId":"233902",
"dioptScore":1,
"bestScore":false,
"goTerms":[
{
"goId":"GO:0005515",
"goTerm":"protein binding",
"goType":0
}
],
"expression":[
{
"tissueId":"EMAPA:17366",
"mgiId":3039600,
"expType":1,
"description":"urinary system"
},
{
"tissueId":"EMAPA:17381",
"mgiId":3039600,
"expType":1,
"description":"reproductive system"
},
{
"tissueId":"EMAPA:35961",
"mgiId":3039600,
"expType":2,
"description":"embryo mesenchyme"
},
{
"tissueId":"EMAPA:36473",
"mgiId":3039600,
"expType":1,
"description":"early conceptus"
}
]
},
{
"geneSymbol":"Kdm2b",
"geneId":"1354737",
"entrezId":"30841",
"dioptScore":1,
"bestScore":false,
"goTerms":[
{
"goId":"GO:0000122",
"goTerm":"negative regulation of transcription from RNA polymerase II promoter",
"goType":1
},
{
"goId":"GO:0000979",
"goTerm":"RNA polymerase II core promoter sequence-specific DNA binding",
"goType":0
},
{
"goId":"GO:0005515",
"goTerm":"protein binding",
"goType":0
},
{
"goId":"GO:0007283",
"goTerm":"spermatogenesis",
"goType":1
},
{
"goId":"GO:0021555",
"goTerm":"midbrain-hindbrain boundary morphogenesis",
"goType":1
},
{
"goId":"GO:0021592",
"goTerm":"fourth ventricle development",
"goType":1
},
{
"goId":"GO:0021670",
"goTerm":"lateral ventricle development",
"goType":1
},
{
"goId":"GO:0021678",
"goTerm":"third ventricle development",
"goType":1
},
{
"goId":"GO:0021993",
"goTerm":"initiation of neural tube closure",
"goType":1
},
{
"goId":"GO:0030307",
"goTerm":"positive regulation of cell growth",
"goType":1
},
{
"goId":"GO:0030900",
"goTerm":"forebrain development",
"goType":1
},
{
"goId":"GO:0030901",
"goTerm":"midbrain development",
"goType":1
},
{
"goId":"GO:0030902",
"goTerm":"hindbrain development",
"goType":1
},
{
"goId":"GO:0043524",
"goTerm":"negative regulation of neuron apoptotic process",
"goType":1
},
{
"goId":"GO:0048596",
"goTerm":"embryonic camera-type eye morphogenesis",
"goType":1
},
{
"goId":"GO:0070544",
"goTerm":"histone H3-K36 demethylation",
"goType":1
},
{
"goId":"GO:1902459",
"goTerm":"positive regulation of stem cell population maintenance",
"goType":1
},
{
"goId":"GO:2000178",
"goTerm":"negative regulation of neural precursor cell proliferation",
"goType":1
}
],
"expression":[
{
"tissueId":"EMAPA:17366",
"mgiId":1354737,
"expType":1,
"description":"urinary system"
},
{
"tissueId":"EMAPA:17381",
"mgiId":1354737,
"expType":1,
"description":"reproductive system"
},
{
"tissueId":"EMAPA:35961",
"mgiId":1354737,
"expType":2,
"description":"embryo mesenchyme"
}
]
},
{
"geneSymbol":"Lrrc29",
"geneId":"2443262",
"entrezId":"234684",
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
{
"tissueId":"EMAPA:16469",
"mgiId":2443262,
"expType":1,
"description":"nervous system"
},
{
"tissueId":"EMAPA:16727",
"mgiId":2443262,
"expType":2,
"description":"respiratory system"
},
{
"tissueId":"EMAPA:16840",
"mgiId":2443262,
"expType":2,
"description":"liver and biliary system"
},
{
"tissueId":"EMAPA:17366",
"mgiId":2443262,
"expType":1,
"description":"urinary system"
},
{
"tissueId":"EMAPA:17381",
"mgiId":2443262,
"expType":1,
"description":"reproductive system"
},
{
"tissueId":"EMAPA:18765",
"mgiId":2443262,
"expType":1,
"description":"hemolymphoid system"
},
{
"tissueId":"EMAPA:35306",
"mgiId":2443262,
"expType":1,
"description":"endocrine system"
}
]
},
{
"geneSymbol":"Fbxl21",
"geneId":"2442921",
"entrezId":"213311",
"dioptScore":1,
"bestScore":false,
"goTerms":[
{
"goId":"GO:0005515",
"goTerm":"protein binding",
"goType":0
},
{
"goId":"GO:0005634",
"goTerm":"nucleus",
"goType":2
},
{
"goId":"GO:0005829",
"goTerm":"cytosol",
"goType":2
},
{
"goId":"GO:0016567",
"goTerm":"protein ubiquitination",
"goType":1
},
{
"goId":"GO:0019005",
"goTerm":"SCF ubiquitin ligase complex",
"goType":2
},
{
"goId":"GO:0043153",
"goTerm":"entrainment of circadian clock by photoperiod",
"goType":1
}
],
"expression":[
{
"tissueId":"EMAPA:16246",
"mgiId":2442921,
"expType":1,
"description":"alimentary system"
},
{
"tissueId":"EMAPA:16469",
"mgiId":2442921,
"expType":1,
"description":"nervous system"
},
{
"tissueId":"EMAPA:17366",
"mgiId":2442921,
"expType":1,
"description":"urinary system"
},
{
"tissueId":"EMAPA:17381",
"mgiId":2442921,
"expType":1,
"description":"reproductive system"
},
{
"tissueId":"EMAPA:35306",
"mgiId":2442921,
"expType":1,
"description":"endocrine system"
}
]
},
{
"geneSymbol":"Fbxl6",
"geneId":"1354705",
"entrezId":"30840",
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
]
}
]
get
Get the predicted rat orthologs of a human gene
get /homolog/rat
Get the predicted rat orthologs of a human gene
Query Parameters
- geneSymbol: required(string)
Specify the human gene symbol that you want to get rat ortholog of
Example:
FBXL4
HTTP status code 200
Body
Media type: application/json
Type: array of object
Items: items
- geneSymbol: required(string)
gene symbol of the ortholog rat gene
- geneId: required(string)
RGD ID of the rat gene
- entrezId: required(integer)
Entrez Gene ID of the rat gene
- dioptScore: required(integer)
DIOPT score that indicates the number of individual ortholog prediction tools that report a given ortholog pair. Maximum 11.
- bestScore: required(boolean)
if this ortholog pair has best scores among all the pairs then
true, otherwise,false. - goTerms: required(array of object)
Experiment based GO terms
Items: items
- goId: required(string)
- goTerms: required(string)
the name of the GO term
- goTypes: required(integer)
0 if molecular function, 1 if biological process, 2 if celluar component
- expression: required(array of object)
Wild type expression information
Items: items
- rgdId: required(integer)
- fpkm: required(number)
- name: required(string)
Organ name
Example:
[
{
"geneSymbol":"Fbxl4",
"geneId":"1305724",
"entrezId":313101,
"dioptScore":10,
"bestScore":true,
"goTerms":[
],
"expression":[
{
"organId":5,
"rgdId":1305724,
"fpkm":6,
"name":"adrenal gland"
},
{
"organId":6,
"rgdId":1305724,
"fpkm":6,
"name":"brain"
},
{
"organId":7,
"rgdId":1305724,
"fpkm":12,
"name":"gastrocnemius"
},
{
"organId":8,
"rgdId":1305724,
"fpkm":3,
"name":"heart"
},
{
"organId":9,
"rgdId":1305724,
"fpkm":7,
"name":"kidney"
},
{
"organId":10,
"rgdId":1305724,
"fpkm":3,
"name":"liver"
},
{
"organId":11,
"rgdId":1305724,
"fpkm":9,
"name":"lung"
},
{
"organId":12,
"rgdId":1305724,
"fpkm":7,
"name":"spleen"
},
{
"organId":13,
"rgdId":1305724,
"fpkm":6,
"name":"thymus"
},
{
"organId":14,
"rgdId":1305724,
"fpkm":7,
"name":"uterus"
}
]
},
{
"geneSymbol":"Fbxl17",
"geneId":"1309773",
"entrezId":316663,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
{
"organId":5,
"rgdId":1309773,
"fpkm":11,
"name":"adrenal gland"
},
{
"organId":6,
"rgdId":1309773,
"fpkm":13,
"name":"brain"
},
{
"organId":7,
"rgdId":1309773,
"fpkm":15,
"name":"gastrocnemius"
},
{
"organId":8,
"rgdId":1309773,
"fpkm":17,
"name":"heart"
},
{
"organId":9,
"rgdId":1309773,
"fpkm":19,
"name":"kidney"
},
{
"organId":10,
"rgdId":1309773,
"fpkm":7,
"name":"liver"
},
{
"organId":11,
"rgdId":1309773,
"fpkm":17,
"name":"lung"
},
{
"organId":12,
"rgdId":1309773,
"fpkm":27,
"name":"spleen"
},
{
"organId":13,
"rgdId":1309773,
"fpkm":17,
"name":"thymus"
},
{
"organId":14,
"rgdId":1309773,
"fpkm":15,
"name":"uterus"
}
]
},
{
"geneSymbol":"Kdm2b",
"geneId":"1310217",
"entrezId":304495,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
{
"organId":5,
"rgdId":1310217,
"fpkm":2,
"name":"adrenal gland"
},
{
"organId":6,
"rgdId":1310217,
"fpkm":4,
"name":"brain"
},
{
"organId":7,
"rgdId":1310217,
"fpkm":3,
"name":"gastrocnemius"
},
{
"organId":8,
"rgdId":1310217,
"fpkm":2,
"name":"heart"
},
{
"organId":9,
"rgdId":1310217,
"fpkm":4,
"name":"kidney"
},
{
"organId":10,
"rgdId":1310217,
"fpkm":2,
"name":"liver"
},
{
"organId":11,
"rgdId":1310217,
"fpkm":7,
"name":"lung"
},
{
"organId":12,
"rgdId":1310217,
"fpkm":12,
"name":"spleen"
},
{
"organId":13,
"rgdId":1310217,
"fpkm":10,
"name":"thymus"
},
{
"organId":14,
"rgdId":1310217,
"fpkm":8,
"name":"uterus"
}
]
},
{
"geneSymbol":"Fbxl6",
"geneId":"1359687",
"entrezId":362941,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
{
"organId":5,
"rgdId":1359687,
"fpkm":4,
"name":"adrenal gland"
},
{
"organId":6,
"rgdId":1359687,
"fpkm":2,
"name":"brain"
},
{
"organId":7,
"rgdId":1359687,
"fpkm":0.8,
"name":"gastrocnemius"
},
{
"organId":8,
"rgdId":1359687,
"fpkm":1,
"name":"heart"
},
{
"organId":9,
"rgdId":1359687,
"fpkm":4,
"name":"kidney"
},
{
"organId":10,
"rgdId":1359687,
"fpkm":3,
"name":"liver"
},
{
"organId":11,
"rgdId":1359687,
"fpkm":4,
"name":"lung"
},
{
"organId":12,
"rgdId":1359687,
"fpkm":8,
"name":"spleen"
},
{
"organId":13,
"rgdId":1359687,
"fpkm":6,
"name":"thymus"
},
{
"organId":14,
"rgdId":1359687,
"fpkm":7,
"name":"uterus"
}
]
},
{
"geneSymbol":"Fbxl13",
"geneId":"1642425",
"entrezId":100125363,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
{
"organId":6,
"rgdId":1642425,
"fpkm":0.6,
"name":"brain"
},
{
"organId":11,
"rgdId":1642425,
"fpkm":4,
"name":"lung"
},
{
"organId":14,
"rgdId":1642425,
"fpkm":0.7,
"name":"uterus"
}
]
},
{
"geneSymbol":"Fbxl21",
"geneId":"1305555",
"entrezId":306750,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
{
"organId":5,
"rgdId":1305555,
"fpkm":0.7,
"name":"adrenal gland"
},
{
"organId":6,
"rgdId":1305555,
"fpkm":1,
"name":"brain"
},
{
"organId":8,
"rgdId":1305555,
"fpkm":0.5,
"name":"heart"
},
{
"organId":9,
"rgdId":1305555,
"fpkm":2,
"name":"kidney"
},
{
"organId":12,
"rgdId":1305555,
"fpkm":0.6,
"name":"spleen"
}
]
},
{
"geneSymbol":"Fbxl19",
"geneId":"1310989",
"entrezId":308999,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
{
"organId":5,
"rgdId":1310989,
"fpkm":3,
"name":"adrenal gland"
},
{
"organId":6,
"rgdId":1310989,
"fpkm":9,
"name":"brain"
},
{
"organId":7,
"rgdId":1310989,
"fpkm":0.8,
"name":"gastrocnemius"
},
{
"organId":8,
"rgdId":1310989,
"fpkm":1,
"name":"heart"
},
{
"organId":9,
"rgdId":1310989,
"fpkm":4,
"name":"kidney"
},
{
"organId":10,
"rgdId":1310989,
"fpkm":1,
"name":"liver"
},
{
"organId":11,
"rgdId":1310989,
"fpkm":6,
"name":"lung"
},
{
"organId":12,
"rgdId":1310989,
"fpkm":6,
"name":"spleen"
},
{
"organId":13,
"rgdId":1310989,
"fpkm":6,
"name":"thymus"
},
{
"organId":14,
"rgdId":1310989,
"fpkm":10,
"name":"uterus"
}
]
},
{
"geneSymbol":"Fbxl12",
"geneId":"1305528",
"entrezId":313782,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
{
"organId":5,
"rgdId":1305528,
"fpkm":4,
"name":"adrenal gland"
},
{
"organId":6,
"rgdId":1305528,
"fpkm":3,
"name":"brain"
},
{
"organId":7,
"rgdId":1305528,
"fpkm":1,
"name":"gastrocnemius"
},
{
"organId":8,
"rgdId":1305528,
"fpkm":2,
"name":"heart"
},
{
"organId":9,
"rgdId":1305528,
"fpkm":3,
"name":"kidney"
},
{
"organId":10,
"rgdId":1305528,
"fpkm":2,
"name":"liver"
},
{
"organId":11,
"rgdId":1305528,
"fpkm":7,
"name":"lung"
},
{
"organId":12,
"rgdId":1305528,
"fpkm":13,
"name":"spleen"
},
{
"organId":13,
"rgdId":1305528,
"fpkm":54,
"name":"thymus"
},
{
"organId":14,
"rgdId":1305528,
"fpkm":7,
"name":"uterus"
}
]
},
{
"geneSymbol":"Kdm2a",
"geneId":"1309419",
"entrezId":361700,
"dioptScore":1,
"bestScore":false,
"goTerms":[
],
"expression":[
{
"organId":5,
"rgdId":1309419,
"fpkm":15,
"name":"adrenal gland"
},
{
"organId":6,
"rgdId":1309419,
"fpkm":14,
"name":"brain"
},
{
"organId":7,
"rgdId":1309419,
"fpkm":9,
"name":"gastrocnemius"
},
{
"organId":8,
"rgdId":1309419,
"fpkm":10,
"name":"heart"
},
{
"organId":9,
"rgdId":1309419,
"fpkm":17,
"name":"kidney"
},
{
"organId":10,
"rgdId":1309419,
"fpkm":11,
"name":"liver"
},
{
"organId":11,
"rgdId":1309419,
"fpkm":29,
"name":"lung"
},
{
"organId":12,
"rgdId":1309419,
"fpkm":45,
"name":"spleen"
},
{
"organId":13,
"rgdId":1309419,
"fpkm":48,
"name":"thymus"
},
{
"organId":14,
"rgdId":1309419,
"fpkm":38,
"name":"uterus"
}
]
}
]